ea0029p213 | Calcium & Vitamin D metabolism | ICEECE2012
Terada Y.
, Shimamura Y.
, Hamada K.
, Inoue K.
, Ogata K.
, Ishihara M.
, Kagawa T.
, Inoue M.
, Fujimoto S.
, Ikebe M.
, Yuasa K.
, Yamanaka S.
, Sugiura T.
, Nishiyama M.
Background: α-Klotho was first identified as an aging gene and was later shown to be a regulator of phosphate metabolism. Fibroblast growth factor 23 (FGF23) is the key regulator of phosphate metabolism. Serum levels of soluble α-Klotho in chronic kidney disease (CKD) patients have not previously been determined, especially in relation with FGF23 and creatinine levels. This study was designed to investigate whether serum soluble α-Klotho levels are modulated by ...